European Journal of Chemistry

Synthesis and antimicrobial evaluation of some 1,2,4-triazolo[1,5-a]pyridine, pyrimidine sulfonamides and sulfinyl derivatives



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Fatma Fakhry Abdel-Motaal
Mohamed Abd-Elmonem Raslan

Abstract

Several new substituted sulfonamides and sulfinyl compound derivatives were obtained by the reaction of 2-thioxo-1,2,4-triazolo[1,5-a]pyridine and pyrimidine thiol derivatives with (2-chloromethyl)benzimidazole and/or (2-chloromethyl)benzooxazole. Structures of the newly synthesized products have been deduced on the basis of spectral and analytical data. The synthesized compounds were screened for their antimicrobial activity.


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Abdel-Motaal, F. F.; Raslan, M. A.-E. Synthesis and Antimicrobial Evaluation of Some 1,2,4-triazolo[1,5-a]pyridine, Pyrimidine Sulfonamides and Sulfinyl Derivatives. Eur. J. Chem. 2014, 5, 481-487.

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