European Journal of Chemistry

One pot synthesis of 1-((1-aryl-1H-1,2,3-triazol-4-yl)methyl)-1H-benzo[d] imidazoles in ionic liquids: Evaluation of antioxidant and antimicrobial activities



Main Article Content

Suresh Seeka
Sirassu Narsimha
Kumaraswamy Battula
Althaf Hussain Shaikh
Savitha Jyostna Tangeda
Vasudeva Reddy Nagavelli

Abstract

In view of pharmacological importance of benzimidazole and 1,2,3-triazole nuclei, we made an effort to synthesize the bi-functional mimic 1,2,3-triazolyl-benzimidazoles through the copper catalyzed azide-alkyne 1,3-dipolar cycloaddition reaction in ionic liquids. The synthesized compounds were characterized by NMR, IR and Mass spectral analysis. The synthesized compounds were screened for antimicrobial and antioxidant activities. A good number of the compounds found to possess potent antioxidant and antimicrobial activities.


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Seeka, S.; Narsimha, S.; Battula, K.; Shaikh, A. H.; Tangeda, S. J.; Nagavelli, V. R. One Pot Synthesis of 1-(1-Aryl-1H-1,2,3-Triazol-4-yl)methyl)-1H-benzo[d] Imidazoles in Ionic Liquids: Evaluation of Antioxidant and Antimicrobial Activities. Eur. J. Chem. 2015, 6, 482-487.

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