European Journal of Chemistry 2016, 7(3), 334-340. doi:10.5155/eurjchem.7.3.334-340.1446

Synthesis, characterization and antimicrobial investigation of Rh(III), Ru(III) and Ag(I) complexes with some derivatives of 3-amino-2-thioxo-2,3-dihydroquinazolin-4(1H)-ones


Ramu Guda (1) , Kumara Swamy Battula (2) , Srujana Muthadi (3) , Sarika Kasarla (4) , Rambabu Palabindela (5) , Rajashekar Korra (6) , Thampu Raja Komuraiah (7) , Mamatha Kasula (8,*)

(1) Department of Chemistry, Kakatiya University, Warangal, 506009, Telangana, India
(2) Department of Chemistry, Kakatiya University, Warangal, 506009, Telangana, India
(3) University College of Pharmaceutical Sciences, Kakatiya University, Warangal, 506009, Telangana, India
(4) Department of Microbiology, Kakatiya University, Warangal, 506009, Telangana, India
(5) Department of Chemistry, Kakatiya University, Warangal, 506009, Telangana, India
(6) Department of Chemistry, Kakatiya University, Warangal, 506009, Telangana, India
(7) Department of Microbiology, Kakatiya University, Warangal, 506009, Telangana, India
(8) Department of Chemistry, Kakatiya University, Warangal, 506009, Telangana, India
(*) Corresponding Author

Received: 10 May 2016, Accepted: 09 Jul 2016, Published: 30 Sep 2016

Abstract


The reaction of 2,3-disubstituted mercapto quinazolines with 2-hydroxy benzaldehyde (HBAMQ) (1), 2-hydroxy naphthaldehyde (HNAMQ) (2), pyridine-2-carboxaldehyde (PMAMQ) (3) and thiophen-2-carboxaldehyde (TMAMQ) (4), and with metals like Rh(III), Ru(III), and Ag(I) in the presence of piperidine resulted in the formation of their respective complexes by physicochemical methods. The newly synthesized complexes were characterized by elemental analysis, magnetic data, and spectroscopic techniques like UV-Visible, IR and 1H NMR, respectively. These compounds were also evaluated for their antimicrobial activities.


Keywords


Synthesis; Piperidine; Complexes; Antimicrobial activity; Mercapto quinazolines; Mononuclear complexes

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DOI: 10.5155/eurjchem.7.3.334-340.1446

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How to cite


Guda, R.; Battula, K.; Muthadi, S.; Kasarla, S.; Palabindela, R.; Korra, R.; Komuraiah, T.; Kasula, M. Eur. J. Chem. 2016, 7(3), 334-340. doi:10.5155/eurjchem.7.3.334-340.1446
Guda, R.; Battula, K.; Muthadi, S.; Kasarla, S.; Palabindela, R.; Korra, R.; Komuraiah, T.; Kasula, M. Synthesis, characterization and antimicrobial investigation of Rh(III), Ru(III) and Ag(I) complexes with some derivatives of 3-amino-2-thioxo-2,3-dihydroquinazolin-4(1H)-ones. Eur. J. Chem. 2016, 7(3), 334-340. doi:10.5155/eurjchem.7.3.334-340.1446
Guda, R., Battula, K., Muthadi, S., Kasarla, S., Palabindela, R., Korra, R., Komuraiah, T., & Kasula, M. (2016). Synthesis, characterization and antimicrobial investigation of Rh(III), Ru(III) and Ag(I) complexes with some derivatives of 3-amino-2-thioxo-2,3-dihydroquinazolin-4(1H)-ones. European Journal of Chemistry, 7(3), 334-340. doi:10.5155/eurjchem.7.3.334-340.1446
Guda, Ramu, Kumara Swamy Battula, Srujana Muthadi, Sarika Kasarla, Rambabu Palabindela, Rajashekar Korra, Thampu Raja Komuraiah, & Mamatha Kasula. "Synthesis, characterization and antimicrobial investigation of Rh(III), Ru(III) and Ag(I) complexes with some derivatives of 3-amino-2-thioxo-2,3-dihydroquinazolin-4(1H)-ones." European Journal of Chemistry [Online], 7.3 (2016): 334-340. Web. 15 Nov. 2019
Guda, Ramu, Battula, Kumara, Muthadi, Srujana, Kasarla, Sarika, Palabindela, Rambabu, Korra, Rajashekar, Komuraiah, Thampu, AND Kasula, Mamatha. "Synthesis, characterization and antimicrobial investigation of Rh(III), Ru(III) and Ag(I) complexes with some derivatives of 3-amino-2-thioxo-2,3-dihydroquinazolin-4(1H)-ones" European Journal of Chemistry [Online], Volume 7 Number 3 (30 September 2016)

DOI Link: https://doi.org/10.5155/eurjchem.7.3.334-340.1446

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