OPEN ACCESS | PEER-REVIEWED | RESEARCH ARTICLE | DOWNLOAD PDF | VIEW FULL-TEXT PDF | TOTAL VIEWS
Synthesis, structural elucidation and X-ray crystallographic studies of 1-(3,5-bis(trifluoromethyl)phenyl)-3-(dimethylamino)prop-2-en-1-one
Stability Nongrum (1) , Susma Das (2) , Shikpika Khanikar (3) , Jai Narain Vishwakarma (4,*)
(1) Organic Research Laboratory, Department of Chemical Science, Assam Don Bosco University, Tapesia Gardens, Kamarkuchi, Sonapur, 782 402 Assam, India
(2) Organic Research Laboratory, Department of Chemical Science, Assam Don Bosco University, Tapesia Gardens, Kamarkuchi, Sonapur, 782 402 Assam, India
(3) Organic Research Laboratory, Department of Chemical Science, Assam Don Bosco University, Tapesia Gardens, Kamarkuchi, Sonapur, 782 402 Assam, India
(4) Organic Research Laboratory, Department of Chemical Science, Assam Don Bosco University, Tapesia Gardens, Kamarkuchi, Sonapur, 782 402 Assam, India
(*) Corresponding Author
Received: 03 Sep 2019 | Revised: 24 Sep 2019 | Accepted: 06 Oct 2019 | Published: 31 Dec 2019 | Issue Date: December 2019
A new enaminone was synthesized by reacting 3,5-bis-(trifluoromethyl)acetophenones and N,N-dimethylformamide dimethyl acetal and its detailed structural and crystalline properties were studied. The crystal data were found to be as C13H11F6NO, monoclinic, space group P21/c (no. 14), a = 8.1556(8) Å, b = 24.877(3) Å, c = 7.6067(7) Å, β = 116.745(6)°, V = 1378.2(3) Å3, Z = 4, T = 293(2) K, μ(MoKα) = 0.150 mm-1, Dcalc = 1.500 g/cm3, 40777 reflections measured (5.594° ≤ 2Θ ≤ 56.786°), 3413 unique (Rint = 0.1040, Rsigma = 0.0584) which were used in all calculations. The final R1 was 0.0771 (I > 2σ(I)) and wR2 was 0.2541 (all data).
Links for Article
| | | | |
| | | | | | |
Article MetricsThis Abstract was viewed 243 times | PDF Article downloaded 73 times
Department of Biotechnology, Government of India, India.
. Musumeci, D.; Irace, C.; Santamaria, R.; Montesarchio, D. Med. Chem. Commun. 2013, 4, 1405-1410.
. Wang, J.; Sanchez-Rosello, M.; Acena, L. J.; Pozo, del C.; Sorochinsky, E. A.; Fustero, S.; Soloshonok, A. V.; Liu, H. Chem. Rev. 2014, 114, 2432-2506.
. Lisi, H.; Xinkan, Y.; Gavin, C. T. J. Org. Chem. 2017, 82, 6192-6201
. Purser, S.; Moore, P. R.; Swallow, S.; Gouverneur, V. Chem. Soc. Rev. 2008, 37, 320-330.
. Champagne, A. P.; Desroches, J.; Hamel, J. D.; Vandamme, M.; Paquin, J. F. Chem. Rev. 2015, 115, 9073-9174.
. Charpentier, J.; Fruh, N.; Togni, A. Chem. Rev. 2015, 115, 650-682.
. Vishwakarma, J. N.; Khanikar, S.; Kalita, U.; Kaping S.; Ray, M. Curr. Chem. Lett. 2018, 7, 35-44.
. Mohamed, A. R.; Omran, A. O. J. Heterocycl. Chem. 2016, 53, 1121-1128.
. Kalita, U.; Kaping, S.; Nongkynrih, R.; Sunn, M.; Boiss, I.; Singha, I. L.; Vishwakarma, J. N. Med. Chem. Res. 2015, 24(6), 2742-2755.
. Kalita, U.; Kaping, S.; Nellanant, J.; Helissey, P.; Vishwakarma, N. J. Heterocyclic Lett. 2014, 4(1), 137-145.
. Bruker, APEX II, Bruker AXS Inc., Madison, WI, USA, 2004.
. Sheldrick, G. M. SHELXS-97 and SHELXL-97, Program for Crystal Structure Solution and Refinement, University of Gottingen, Gottingen, 1997
. Farrugia, L. J. J. Appl. Crystallogr. 1999, 32, 837-838.
The Supplementary Material for this article can be found online at: Supplementary files
How to cite
DOI Link: https://doi.org/10.5155/eurjchem.10.4.381-385.1922
| | | | |
| | | | | |
Save to Zotero Save to Mendeley
European Journal of Chemistry 2019, 10(4), 381-385 | doi: https://doi.org/10.5155/eurjchem.10.4.381-385.1922 | Get rights and content
- There are currently no refbacks.
Copyright (c) 2019 Authors
This work is published and licensed by Atlanta Publishing House LLC, Atlanta, GA, USA. The full terms of this license are available at http://www.eurjchem.com/index.php/eurjchem/pages/view/terms and incorporate the Creative Commons Attribution-Non Commercial (CC BY NC) (International, v4.0) License (http://creativecommons.org/licenses/by-nc/4.0). By accessing the work, you hereby accept the Terms. This is an open access article distributed under the terms and conditions of the CC BY NC License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited without any further permission from Atlanta Publishing House LLC (European Journal of Chemistry). No use, distribution or reproduction is permitted which does not comply with these terms. Permissions for commercial use of this work beyond the scope of the License (http://www.eurjchem.com/index.php/eurjchem/pages/view/terms) are administered by Atlanta Publishing House LLC (European Journal of Chemistry).
© Copyright 2010 - 2020 • Atlanta Publishing House LLC • All Right Reserved.
The opinions expressed in all articles published in European Journal of Chemistry are those of the specific author(s), and do not necessarily reflect the views of Atlanta Publishing House LLC, or European Journal of Chemistry, or any of its employees.
Copyright 2010-2020 Atlanta Publishing House LLC. All rights reserved. This site is owned and operated by Atlanta Publishing House LLC whose registered office is 2850 Smith Ridge Trce Peachtree Cor GA 30071-2636, USA. Registered in USA.