European Journal of Chemistry

A simple stereoselective synthesis of (+)-[6]-gingerdiol

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Published: Sep 30, 2013
DOI: https://doi.org/10.5155/eurjchem.4.3.191-194.768
Keywords:
Vanilline, Gingerdiol, Syn-epoxy alcohol, Maruoka allylation, Electrophilic cyclization, Stereoselective synthesis
Section
Research Article
Issue
Vol. 4 No. 3 (2013): September 2013
Dates
Received 2013-03-11
Accepted 2013-03-26
Published 2013-09-30


Main Article Content

Rathod Aravind Kumar
Organic Chemistry Division-I, CSIR-Indian Institute of Chemical Technology, Hyderabad-500007, India
Jajula Kashanna
Organic Chemistry Division-I, CSIR-Indian Institute of Chemical Technology, Hyderabad-500007, India
Paramesh Jangili
Organic Chemistry Division-I, CSIR-Indian Institute of Chemical Technology, Hyderabad-500007, India
Biswanath Das
Organic Chemistry Division-I, CSIR-Indian Institute of Chemical Technology, Hyderabad-500007, India

Abstract

A simple stereoselective synthesis of (+)-[6]-gingerdiol has been accomplished starting from vanillin. The synthetic sequence involves Mouroka allylation, diasterioselective iodine induced electrophilic cyclization and ring-opening of an epoxide as the key steps.

4_3_191_194

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Kumar, R. A.; Kashanna, J.; Jangili, P.; Das, B. A Simple Stereoselective Synthesis of (+)-[6]-Gingerdiol. Eur. J. Chem. 2013, 4, 191-194.

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