European Journal of Chemistry

Synthesis and characterization of diaza analogues of podophyllotoxin

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Published: Sep 30, 2013
DOI: https://doi.org/10.5155/eurjchem.4.3.235-239.782
Keywords:
Chalcones, Tetralones, Ethylformate, Sodium hydride, Hydrazine hydrate, Cyclopropyl ketones
Section
Research Article
Issue
Vol. 4 No. 3 (2013): September 2013
Dates
Received 2013-03-23
Accepted 2013-04-20
Published 2013-09-30


Main Article Content

Yeriyur Basavaiah Basavaraju
Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore-570006, Karnataka, India
Basavaiah Umesha
Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore-570006, Karnataka, India

Abstract

In an attempt to synthesize the novel diaza analogues of podophyllotoxin (7a-d) in five step reactions. The synthesis of title compounds has been achieved from tetralones, which were formylated with ethylformate; prepared via cyclization with hydrazine hydrate. Furthermore, these newly synthesized compounds were characterized by spectral and elemental analysis data.

4_3_235_239

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Basavaraju, Y. B.; Umesha, B. Synthesis and Characterization of Diaza Analogues of Podophyllotoxin. Eur. J. Chem. 2013, 4, 235-239.

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