European Journal of Chemistry

Stabilization of 5-aminolevulinic acid by the zinc(II) ion in an aqueous solution

Article Sidebar

PDF
Published: Dec 22, 2010
DOI: https://doi.org/10.5155/eurjchem.1.4.373-376.101
Keywords:
5-aminolevulinic acid, Zinc(II) ion, UV-VIS absorption spectra, NMR, pH
Section
Short Communication
Issue
Vol. 1 No. 4 (2010): December 2010
Dates
Received 2010-05-06
Accepted 2010-06-22
Published 2010-12-22


Main Article Content

Hiroshi Sakiyama
Department of Material and Biological Chemistry, Faculty of Science, Yamagata University, Kojirakawa, Yamagata, JP-990-8560, Japan
Hidetatsu Inoue
Department of Material and Biological Chemistry, Faculty of Science, Yamagata University, Kojirakawa, Yamagata, JP-990-8560, Japan
Md.Kudrat-E-Zahan Md.Kudrat-E-Zahan
Department of Material and Biological Chemistry, Faculty of Science, Yamagata University, Kojirakawa, Yamagata, JP-990-8560, Japan
Shoichi Hueki
Cosmo Oil Co., Ltd., Shibaura, Minatoku, Tokyo, JP-105-8528, Japan
Naohisa Tachiya
Cosmo Oil Co., Ltd., Shibaura, Minatoku, Tokyo, JP-105-8528, Japan
Yuzo Nishida
Department of Material and Biological Chemistry, Faculty of Science, Yamagata University, Kojirakawa, Yamagata, JP-990-8560, Japan

Abstract

It is known that 5-aminolevulinic acid (5-ALA) is not stable in an aqueous solution because of the auto-condensation reaction between two 5-ALA molecules; however, in this study, 5-ALA was stabilized by the zinc(II) ion in an aqueous solution of neutral pH. This stabilization effect was ascertained by UV-Vis Spectroscopy and 1H and 13C NMR Spectroscopy.

1_4_373_376_800


icon graph This Abstract was viewed 1354 times | icon graph Article PDF downloaded 773 times

How to Cite
(1)
Sakiyama, H.; Inoue, H.; Md.Kudrat-E-Zahan, M.-E.-Z.; Hueki, S.; Tachiya, N.; Nishida, Y. Stabilization of 5-Aminolevulinic Acid by the zinc(II) Ion in an Aqueous Solution. Eur. J. Chem. 2010, 1, 373-376.

Article Details

Share
Links for Article


Crossref - Scopus - Google - European PMC
Crossref
Scopus
Google Scholar
Europe PMC
References

[1]. Shemin, D.; Russell, C. S. J. Am. Chem. Soc. 1953, 75, 4873–4874.
doi:10.1021/ja01115a546

[2]. Jaffe, E. K.; Rajagopalan, J. S. Bioinorg. Chem. 1990, 18, 381–394.

[3]. Novo, M.; Hüttmann, G.; Diddens, H. J. Photochem. Photobiol. B. Biol. 1996, 34, 143–148.
doi:10.1016/1011-1344(96)07285-5

[4]. Elfsson, B.; Wallin, I.; Eksborg, S.; Rudaeus, K.; Ros, A. M.; Ehrsson, H. Eur. J. Pharm. Sci. 1998, 7, 87–91.
doi:10.1016/S0928-0987(98)00009-8

[5]. Bunke, A.; Zerbe, O.; Schmid, H.; Burmeister, G.; Merkle, H. P.; Gander, B. J. Pharm. Sci. 2000, 89, 1335–1341.
doi:10.1002/1520-6017(200010)89:10<1335::AID-JPS11>3.0.CO;2-#

[6]. Gadmar, Ø. B.; Moan, J.; Scheie, E.; Ma, L. W.; Peng, Q. J. Photochem. Photobiol. B: Biol. 2002, 67, 187–193.
doi:10.1016/S1011-1344(02)00278-6

[7]. Nishikawa, S.; Watanabe, K.; Tanaka, T.; Miyachi, N.; Hotta, Y.; Murooka, Y. J. Biosci. Bioeng. 1999, 87, 798–804.
doi:10.1016/S1389-1723(99)80156-X

Supporting Agencies

Most read articles by the same author(s)
TrendMD

Dimensions - Altmetric - scite_ - PlumX

Downloads and views

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...
License Terms

License Terms

by-nc

Copyright © 2025 by Authors. This work is published and licensed by Atlanta Publishing House LLC, Atlanta, GA, USA. The full terms of this license are available at https://www.eurjchem.com/index.php/eurjchem/terms and incorporate the Creative Commons Attribution-Non Commercial (CC BY NC) (International, v4.0) License (http://creativecommons.org/licenses/by-nc/4.0). By accessing the work, you hereby accept the Terms. This is an open access article distributed under the terms and conditions of the CC BY NC License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited without any further permission from Atlanta Publishing House LLC (European Journal of Chemistry). No use, distribution, or reproduction is permitted which does not comply with these terms. Permissions for commercial use of this work beyond the scope of the License (https://www.eurjchem.com/index.php/eurjchem/terms) are administered by Atlanta Publishing House LLC (European Journal of Chemistry).