European Journal of Chemistry 2010, 1(4), 373-376 | doi: https://doi.org/10.5155/eurjchem.1.4.373-376.101 | Get rights and content

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Stabilization of 5-aminolevulinic acid by the zinc(II) ion in an aqueous solution


Hiroshi Sakiyama (1,*) , Hidetatsu Inoue (2) , Md.Kudrat-E-Zahan Md.Kudrat-E-Zahan (3) , Shoichi Hueki (4) , Naohisa Tachiya (5) , Yuzo Nishida (6)

(1) Department of Material and Biological Chemistry, Faculty of Science, Yamagata University, Kojirakawa, Yamagata, JP-990-8560, Japan
(2) Department of Material and Biological Chemistry, Faculty of Science, Yamagata University, Kojirakawa, Yamagata, JP-990-8560, Japan
(3) Department of Material and Biological Chemistry, Faculty of Science, Yamagata University, Kojirakawa, Yamagata, JP-990-8560, Japan
(4) Cosmo Oil Co., Ltd., Shibaura, Minatoku, Tokyo, JP-105-8528, Japan
(5) Cosmo Oil Co., Ltd., Shibaura, Minatoku, Tokyo, JP-105-8528, Japan
(6) Department of Material and Biological Chemistry, Faculty of Science, Yamagata University, Kojirakawa, Yamagata, JP-990-8560, Japan
(*) Corresponding Author

Received: 06 May 2010 | Revised: 04 Sep 2010 | Accepted: 22 Jun 2010 | Published: 22 Dec 2010 | Issue Date: December 2010

Abstract


It is known that 5-aminolevulinic acid (5-ALA) is not stable in an aqueous solution because of the auto-condensation reaction between two 5-ALA molecules; however, in this study, 5-ALA was stabilized by the zinc(II) ion in an aqueous solution of neutral pH. This stabilization effect was ascertained by UV-Vis Spectroscopy and 1H and 13C NMR Spectroscopy.

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Keywords


5-aminolevulinic acid; Zinc(II) ion; UV-VIS absorption spectra; NMR; pH

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DOI: 10.5155/eurjchem.1.4.373-376.101

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Citations

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[1]. Phattanit Tripetch, Chaleeda Borompichaichartkul, Kiattisak Duangmal, George Srzednicki
Entrapment of 5‐aminolevulinic acid under edible composite film of konjac glucomannan and chitosan
Engineering in Life Sciences  16(4), 386, 2016
DOI: 10.1002/elsc.201500111
/

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How to cite


Sakiyama, H.; Inoue, H.; Md.Kudrat-E-Zahan, M.; Hueki, S.; Tachiya, N.; Nishida, Y. Eur. J. Chem. 2010, 1(4), 373-376. doi:10.5155/eurjchem.1.4.373-376.101
Sakiyama, H.; Inoue, H.; Md.Kudrat-E-Zahan, M.; Hueki, S.; Tachiya, N.; Nishida, Y. Stabilization of 5-aminolevulinic acid by the zinc(II) ion in an aqueous solution. Eur. J. Chem. 2010, 1(4), 373-376. doi:10.5155/eurjchem.1.4.373-376.101
Sakiyama, H., Inoue, H., Md.Kudrat-E-Zahan, M., Hueki, S., Tachiya, N., & Nishida, Y. (2010). Stabilization of 5-aminolevulinic acid by the zinc(II) ion in an aqueous solution. European Journal of Chemistry, 1(4), 373-376. doi:10.5155/eurjchem.1.4.373-376.101
Sakiyama, Hiroshi, Hidetatsu Inoue, Md.Kudrat-E-Zahan Md.Kudrat-E-Zahan, Shoichi Hueki, Naohisa Tachiya, & Yuzo Nishida. "Stabilization of 5-aminolevulinic acid by the zinc(II) ion in an aqueous solution." European Journal of Chemistry [Online], 1.4 (2010): 373-376. Web. 28 Sep. 2023
Sakiyama, Hiroshi, Inoue, Hidetatsu, Md.Kudrat-E-Zahan, Md.Kudrat-E-Zahan, Hueki, Shoichi, Tachiya, Naohisa, AND Nishida, Yuzo. "Stabilization of 5-aminolevulinic acid by the zinc(II) ion in an aqueous solution" European Journal of Chemistry [Online], Volume 1 Number 4 (22 December 2010)

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DOI Link: https://doi.org/10.5155/eurjchem.1.4.373-376.101


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