European Journal of Chemistry

Eco-friendly and simple synthesis of some non-natural flavones through chalcones

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Published: Sep 30, 2018
DOI: https://doi.org/10.5155/eurjchem.9.3.236-240.1732
Keywords:
Iodine, Flavones, Chalcones, Sulfuric acid, Microwave chemistry, Conventional synthesis
Section
Research Article
Issue
Vol. 9 No. 3 (2018): September 2018
Dates
Received 2018-05-08
Accepted 2018-06-06
Published 2018-09-30
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Main Article Content

Mohammad Saidur Rahman
Department of Chemistry, Faculty of Mathematical and Physical Sciences, Jahangirnagar University, Savar, Dhaka-1342, Bangladesh
http://orcid.org/0000-0003-3747-2098
Sayeda Shakila Alam
Department of Chemistry, Faculty of Mathematical and Physical Sciences, Jahangirnagar University, Savar, Dhaka-1342, Bangladesh
http://orcid.org/0000-0001-6454-7118
Kamrunnahar Happy
Department of Chemistry, Faculty of Mathematical and Physical Sciences, Jahangirnagar University, Savar, Dhaka-1342, Bangladesh
http://orcid.org/0000-0002-0026-1855
Mohammad Mamun Hossain
Department of Chemistry, Faculty of Mathematical and Physical Sciences, Jahangirnagar University, Savar, Dhaka-1342, Bangladesh
http://orcid.org/0000-0002-7712-2482
Mohammad Khademul Islam
Department of Chemistry, Faculty of Science, Mawlana Bhashani Science and Technology University, Santosh, Tangail-1902, Bangladesh
http://orcid.org/0000-0002-3819-4977
Foni Bushon Biswas
Department of Chemistry, Faculty of Science, University of Chittagong, Chittagong-4331, Bangladesh
http://orcid.org/0000-0002-0935-8530

Abstract

A distinctive feature of polyphenolics is the possession of biological properties such as antioxidant and antimicrobial activities. Simple synthesis and study about such important class of compounds and their analogs are very important to enhance the understanding of their role in human health and diseases. Accordingly, a series of chalcones (2a-f) have been synthesized by Claisen-Schmidt condensation reaction with required acetophenones and aromatic aldehydes in high yields. The conversion of chalcones to the corresponding flavones (1a-g) taking minimal amount of dimethyl sulfoxide with iodine in presence of sulfuric acid was carried out under microwave conditions in high yields.


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How to Cite
(1)
Rahman, M. S.; Alam, S. S.; Happy, K.; Hossain, M. M.; Islam, M. K.; Biswas, F. B. Eco-Friendly and Simple Synthesis of Some Non-Natural Flavones through Chalcones. Eur. J. Chem. 2018, 9, 236-240.

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Supporting Agencies

The Ministry of Science and Technology, Government of the People’s Republic of Bangladesh.
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