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Synthesis, characterization and crystal structure of ethyl 4-(3-chloro benzamido)benzoate


Aamer Saeed (1,*) , Hummera Rafique (2) , Ulrich Flörke (3)

(1) Department of Chemistry, Quaid-I-Azam University, Islamabad, PK-45320, Pakistan
(2) Department of Chemistry, Quaid-I-Azam University, Islamabad, PK-45320, Pakistan
(3) Department Chemie, Fakultät fur Naturwissenschaften, Universitat Paderborn, Warburgerstrasse 100, Paderborn, D-33098, Germany
(*) Corresponding Author

Received: 16 Jul 2010 | Accepted: 07 Aug 2010 | Published: 22 Dec 2010 | Issue Date: December 2010

Abstract


The title compound was efficiently synthesized in two steps starting from esterification of 4-aminobenzoic acid followed by amidation with 3-chlorobenzoyl chloride in dry tetrahydrofuran. The structure was confirmed by spectroscopic data and elemental analysis. The molecular structure was determined from single crystal X-ray diffraction data. It crystallizes in the triclinic space group P-1 with Z = 2 and unit cell dimensions a = 5.2941(15) Å, b = 8.157(2) Å, c = 16.238(4) Å, α = 82.682(6)°, β = 84.481(6)°, γ = 80.100(6)° and V = 683.2(3) Å3.

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Keywords


Ethyl 4-(3-chlorobenzamido)benzoate; Crystal structure; Synthesis; Characterization

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DOI: 10.5155/eurjchem.1.4.289-290.207

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Citations

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[1]. G. Oros, M. Szőgyi, T. Cserháti
RELATIONSHIP BETWEEN THE CALCULATED PHYSICOCHEMICAL PARAMETERS AND REVERSED-PHASE THIN-LAYER CHROMATOGRAPHIC RETENTION BEHAVIOR OF ALKOXY-PHENYLBENZAMIDE DERIVATIVES
Journal of Liquid Chromatography & Related Technologies  35(10), 1314, 2012
DOI: 10.1080/10826076.2012.676948
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Supporting information


The Supplementary Material for this article can be found online at: Supplementary files

How to cite


Saeed, A.; Rafique, H.; Flörke, U. Eur. J. Chem. 2010, 1(4), 289-290. doi:10.5155/eurjchem.1.4.289-290.207
Saeed, A.; Rafique, H.; Flörke, U. Synthesis, characterization and crystal structure of ethyl 4-(3-chloro benzamido)benzoate. Eur. J. Chem. 2010, 1(4), 289-290. doi:10.5155/eurjchem.1.4.289-290.207
Saeed, A., Rafique, H., & Flörke, U. (2010). Synthesis, characterization and crystal structure of ethyl 4-(3-chloro benzamido)benzoate. European Journal of Chemistry, 1(4), 289-290. doi:10.5155/eurjchem.1.4.289-290.207
Saeed, Aamer, Hummera Rafique, & Ulrich Flörke. "Synthesis, characterization and crystal structure of ethyl 4-(3-chloro benzamido)benzoate." European Journal of Chemistry [Online], 1.4 (2010): 289-290. Web. 3 Dec. 2022
Saeed, Aamer, Rafique, Hummera, AND Flörke, Ulrich. "Synthesis, characterization and crystal structure of ethyl 4-(3-chloro benzamido)benzoate" European Journal of Chemistry [Online], Volume 1 Number 4 (22 December 2010)

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DOI Link: https://doi.org/10.5155/eurjchem.1.4.289-290.207


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