European Journal of Chemistry

Synthesis of new curcumin analogues from Claisen-Schmidt condensation

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Nouara Ziani
Assia Sid
Albert Demonceau
Quentin Willem
Benjamin Dassonneville
Kaddour Lamara


A series of new curcumin analogues were obtained by Claisen-Schmidt condensation of substituted benzaldehydes with cyclohexanone derivatives using the ratio of 1:2 of ketone to aldehyde in dilute ethanolic solution under base catalyzed (NaOH) conditions at room temperature in good yields. The structures of the synthesized compounds were confirmed by data of IR, 1H NMR, and 13C NMR spectra.


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Ziani, N.; Sid, A.; Demonceau, A.; Willem, Q.; Dassonneville, B.; Lamara, K. Synthesis of New Curcumin Analogues from Claisen-Schmidt Condensation. Eur. J. Chem. 2013, 4, 146-148.

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Supporting Agencies

Laboratory of Applied Chemistry and Materials Technology, Chemistry Institute, University Larbi Ben M’hidi of Oum El Bouaghi, Rue de Constantine, 04000, Algeria

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