European Journal of Chemistry

Microwave assisted synthesis of new curcumin analogues conjugated dihydro-4-pyridones

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Published: Jun 30, 2015
DOI: https://doi.org/10.5155/eurjchem.6.2.131-134.1177
Keywords:
Curcumin, Amine acetate, Green chemistry, Dihydropyridones, Montmorillonite K-10, Microwave-assisted synthesis
Section
Research Article
Issue
Vol. 6 No. 2 (2015): June 2015
Dates
Received 2014-11-07
Accepted 2015-01-11
Published 2015-06-30


Main Article Content

Maitham Najim Aboud
Department of Chemistry, College of Education of Pure Sciences, University of Basrah, 61001, Basrah, Iraq
Bahjat Ali Saeed
Department of Chemistry, College of Education of Pure Sciences, University of Basrah, 61001, Basrah, Iraq
Rita Sabah Elias
Department of Pharmaceutical Chemistry, college of Pharmacy, University of Basrah, 61001, Basrah, Iraq

Abstract

New curcumin analogues, conjugated dihydro-4-pyridones were synthesized via reaction of curcumin with primary amines or amine acetates under microwave irradiation. Montmorillonite K-10 was used as a catalyst and reaction times within the period 60-90 s. The synthesized compounds were characterized on the basis of their IR, UV-Vis, 1H, 13C NMR and mass spectra.


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How to Cite
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Aboud, M. N.; Saeed, B. A.; Elias, R. S. Microwave Assisted Synthesis of New Curcumin Analogues Conjugated Dihydro-4-Pyridones. Eur. J. Chem. 2015, 6, 131-134.

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References

[1]. Chou, S. S. P.; Wu, C. J. J. Tetrahedron 2012, 68, 1185-1191.
http://dx.doi.org/10.1016/j.tet.2011.11.060

[2]. Kuethe, J. T.; Comins, D. L. Tetrahedron Lett. 2004, 69, 4179-4182.

[3]. Comins, D. L.; Sahn, J. J. Org. Lett. 2005, 7, 5227-5228.
http://dx.doi.org/10.1021/ol052068v

[4]. Avenoza, A.; Busto, J. H.; Cativiela, C.; Corazana, F.; Peregrina, J. M.; Zurbano, M. M. J. Org. Chem. 2002, 67, 598-601.
http://dx.doi.org/10.1021/jo016186h

[5]. Pepe, A.; Pamment, M.; Kim, Y. S.; Lee, S.; Lee, M. J.; Beebe, K.; Filikov, A.; Neckers, L.; Trepel, J. B.; Malhotra, S. V. J. Med. Chem. 2013, 56, 8280-8297.
http://dx.doi.org/10.1021/jm301714s

[6]. Comins, D. L.; Zhang, Y.; Joseph, S. P. J. Org. Chem. 1999, 1, 657-659.

[7]. Comins, D. L.; Kueth, J. T.; Hong, H.; Lakner, F. J. J. Am. Chem. Soc. 1999, 121, 2651-2651.
http://dx.doi.org/10.1021/ja990024+

[8]. Comins, D. L.; Ollinger, G. C. Tetrahedron Lett. 2001, 42, 4115-4118.
http://dx.doi.org/10.1016/S0040-4039(01)00690-6

[9]. Young, D. W.; Comins, D. L. Org. Lett. 2005, 7, 5661-566.
http://dx.doi.org/10.1021/ol052313a

[10]. McCall, W. S.; Grillo, T. A.; Comins, D. L. J. Org. Chem. 2008, 73, 9744-9751.
http://dx.doi.org/10.1021/jo802029y

[11]. Waldman, H.; Braun, M. J. Org. Chem. 1992, 57, 4444-4451.
http://dx.doi.org/10.1021/jo00042a027

[12]. Huang, Y.; Rawal, V. H. Org. Lett. 2000, 2, 3321-3323.
http://dx.doi.org/10.1021/ol006404d

[13]. Alaimo, P. J.; O'Brien, R.; Johanson, A. W.; Slauson, R.; O'Brien, I. M. Org. Lett. 2008, 10, 5111-5114.
http://dx.doi.org/10.1021/ol801911f

[14]. McDonald, F. K.; Burnell, D. J. J. Org. Chem. 2009, 74, 6973-6979.
http://dx.doi.org/10.1021/jo901355e

[15]. Park, Y.; Park, E.; Jung, H.; Lee, Y. J.; Jew, S. S.; Park, H. G. Tetrahedron 2011, 67, 1166-1170.
http://dx.doi.org/10.1016/j.tet.2010.12.002

[16]. Saito, A.; Kasai, J.; Odaira, Y.; Fukaya, H.; Hanzawa, Y. J. Org. Chem. 2009, 74, 5644-5647.
http://dx.doi.org/10.1021/jo900857c

[17]. Dong, D.; Bi, X.; Liu, Q.; Cong, F. Chem. Commun. 2005, 28, 3580-3582.
http://dx.doi.org/10.1039/b505569e

[18]. Donhoe, T. J.; Conolly, M. J.; Walton, L. Org. Lett. 2009, 11, 5562-5565.
http://dx.doi.org/10.1021/ol902402v

[19]. Donohoe, T. J.; Conolly, M. J.; Rathi, A. H.; Walton, L. Org. Lett., 2011, 13, 2074-2077.
http://dx.doi.org/10.1021/ol200478p

[20]. Robinson, E. R. T.; Fallan, C.; Simal, C.; Slawin, A. M. Z.; Smith, A. D. Chem. Sci. 2013, 4, 2193-2200.
http://dx.doi.org/10.1039/c3sc50199j

[21]. Elias, R. S.; Saeed, B. A.; Saour, K. Y.; Al-Masoudi, N. A. Tetrahedron Lett. 2008, 49, 3049-3051.
http://dx.doi.org/10.1016/j.tetlet.2008.03.064

[22]. Saeed, B. A.; Radhi, W. A.; Elias, R. S. Tetrahedron Lett. 2010, 51, 2798-2800.

[23]. Saeed, B. A.; Elias, R. S.; Radhi, W. A. Molecules 2010, 15, 8425-8430.
http://dx.doi.org/10.3390/molecules15118425

[24]. Feng, J. Y.; Liu, Z. Q. J. Agric. Food Chem. 2009, 5, 11041-11046.
http://dx.doi.org/10.1021/jf902244g

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