European Journal of Chemistry

One pot synthesis of 1-((1-aryl-1H-1,2,3-triazol-4-yl)methyl)-1H-benzo[d] imidazoles in ionic liquids: Evaluation of antioxidant and antimicrobial activities

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Published: Dec 31, 2015
DOI: https://doi.org/10.5155/eurjchem.6.4.482-487.1325
Keywords:
Ionic liquid, Benzimidazole, 1, 2, 3-Triazoles, One pot synthesis, Antioxidant activity, Antimicrobial activity
Section
Research Article
Issue
Vol. 6 No. 4 (2015): December 2015
Dates
Received 2015-09-18
Accepted 2015-10-18
Published 2015-12-31


Main Article Content

Suresh Seeka
Department of Chemistry, KakatiyaUniversity, Warangal, TS, 506009, India
Sirassu Narsimha
Department of Chemistry, KakatiyaUniversity, Warangal, TS, 506009, India
Kumaraswamy Battula
Department of Chemistry, KakatiyaUniversity, Warangal, TS, 506009, India
Althaf Hussain Shaikh
Department of Biotechnology, Kakatiya University, Warangal, TS, 506009, India
Savitha Jyostna Tangeda
Department of Chemistry, KakatiyaUniversity, Warangal, TS, 506009, India
Vasudeva Reddy Nagavelli
Department of Chemistry, KakatiyaUniversity, Warangal, TS, 506009, India

Abstract

In view of pharmacological importance of benzimidazole and 1,2,3-triazole nuclei, we made an effort to synthesize the bi-functional mimic 1,2,3-triazolyl-benzimidazoles through the copper catalyzed azide-alkyne 1,3-dipolar cycloaddition reaction in ionic liquids. The synthesized compounds were characterized by NMR, IR and Mass spectral analysis. The synthesized compounds were screened for antimicrobial and antioxidant activities. A good number of the compounds found to possess potent antioxidant and antimicrobial activities.


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Seeka, S.; Narsimha, S.; Battula, K.; Shaikh, A. H.; Tangeda, S. J.; Nagavelli, V. R. One Pot Synthesis of 1-(1-Aryl-1H-1,2,3-Triazol-4-yl)methyl)-1H-benzo[d] Imidazoles in Ionic Liquids: Evaluation of Antioxidant and Antimicrobial Activities. Eur. J. Chem. 2015, 6, 482-487.

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