

Synthesis, structural characterization and biological properties of Cu(II), Ni(II), Mn(II), Zn(II) and VO(II) complexes of tetradentate Schiff bases
Subramanian Vedanayaki (1,*)


(1) Department of Chemistry, Kandaswami Kandar’s College, Paramathi Velur, Tamilnadu, 638182, India
(2) Chemical Division, Mettur Thermal Power Station, Mettur Dam, Tamilnadu, 636406, India
(*) Corresponding Author
Received: 28 Apr 2016 | Revised: 25 Jun 2016 | Accepted: 02 Jul 2016 | Published: 30 Sep 2016 | Issue Date: September 2016
Abstract
New binucleating Cu(II), Ni(II), Mn(II), Zn(II) and VO(II) complexes of the prepared ligands with N4 donor were synthesized. The ligands are obtained by the condensation of para-phenylenediamine with diacetylmonoxime and benzilmonoxime. The synthesized ligands and their metal complexes were characterized by elemental analysis and various spectroscopic techniques. The Cu(II), Ni(II) complexes were square planar, VO(II) complex was square pyramidal, whereas Mn(II), Zn(II) complexes were of tedrahedral geometry. Both the ligands and their metal complexes were screened for their antibacterial and antifungal activities by minimum inhibitory concentration method. The results showed that the metal complexes were found to be more active than free ligand. The DNA binding capacities of all the complexes were analyzed by using UV absorption spectra. The DNA cleaving capacities of all complexes were analyzed by agarose gel electrophoresis method against pBR322 DNA.
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DOI: 10.5155/eurjchem.7.3.368-374.1443
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Funding information
University Grant Commission (MRP-5388/14 (SERO/UGC), March 2014, Com.code TNPE004), Hyderabad, India.
Citations
[1]. P. Priya, S. Vedanayaki, P. Jayaseelan
Synthesis, Spectral Characterization and Biological Evaluation of Schiff Base Metal Complexes Derived from Aniline Derivative
Asian Journal of Chemistry 31(9), 2095, 2019
DOI: 10.14233/ajchem.2019.22129

[2]. Victor Cardoso Campideli, Jerica Margely Montilla-Suárez, Tiago Almeida Silva, Dalila Chaves Sicupira, Katia Mara Oliveira, Rodrigo Souza Correa
Exploring DNA-interaction and molecular structure of ruthenium/1,2-bis-(diphenylphosphino)ethane)-based complex
European Journal of Chemistry 14(2), 193, 2023
DOI: 10.5155/eurjchem.14.2.193-201.2402

[3]. Karthik Somasundaram, Gomathi Thulasimani, Vedanayaki Subramaniam
Synthesis,Characterization, biocidal, Anti-diabetic, Anti-inflammatory and Anti-Cancer(MCF-7) Studies of Schiff base ligand and its metal (II) complexes
Oriental Journal Of Chemistry 37(1), 58, 2021
DOI: 10.13005/ojc/370107

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