Synthesis, characterization and antimicrobial investigation of Rh(III), Ru(III) and Ag(I) complexes with some derivatives of 3-amino-2-thioxo-2,3-dihydroquinazolin-4(1H)-ones | European Journal of Chemistry

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Published: Sep 30, 2016

DOI: https://doi.org/10.5155/eurjchem.7.3.334-340.1446

Keywords:

Synthesis, Piperidine, Complexes, Antimicrobial activity, Mercapto quinazolines, Mononuclear complexes

Section

Research Article

Issue

Vol. 7 No. 3 (2016): September 2016

Dates

Received 2016-05-10
Accepted 2016-07-09
Published 2016-09-30

Ramu Guda

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Department of Chemistry, Kakatiya University, Warangal, 506009, Telangana, India

Kumara Swamy Battula

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Department of Chemistry, Kakatiya University, Warangal, 506009, Telangana, India

Srujana Muthadi

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University College of Pharmaceutical Sciences, Kakatiya University, Warangal, 506009, Telangana, India

Sarika Kasarla

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Department of Microbiology, Kakatiya University, Warangal, 506009, Telangana, India

Rambabu Palabindela

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Department of Chemistry, Kakatiya University, Warangal, 506009, Telangana, India

Rajashekar Korra

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Department of Chemistry, Kakatiya University, Warangal, 506009, Telangana, India

Thampu Raja Komuraiah

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Department of Microbiology, Kakatiya University, Warangal, 506009, Telangana, India

Mamatha Kasula

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Department of Chemistry, Kakatiya University, Warangal, 506009, Telangana, India

Abstract

The reaction of 2,3-disubstituted mercapto quinazolines with 2-hydroxy benzaldehyde (HBAMQ) (1), 2-hydroxy naphthaldehyde (HNAMQ) (2), pyridine-2-carboxaldehyde (PMAMQ) (3) and thiophen-2-carboxaldehyde (TMAMQ) (4), and with metals like Rh(III), Ru(III), and Ag(I) in the presence of piperidine resulted in the formation of their respective complexes by physicochemical methods. The newly synthesized complexes were characterized by elemental analysis, magnetic data, and spectroscopic techniques like UV-Visible, IR and ¹H NMR, respectively. These compounds were also evaluated for their antimicrobial activities.

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Guda, R.; Battula, K. S.; Muthadi, S.; Kasarla, S.; Palabindela, R.; Korra, R.; Komuraiah, T. R.; Kasula, M. Synthesis, Characterization and Antimicrobial Investigation of Rh(III), Ru(III) and Ag(I) Complexes With Some Derivatives of 3-Amino-2-Thioxo-2,3-Dihydroquinazolin-4(1H)-Ones. Eur. J. Chem. 2016, 7, 334-340.

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Supporting Agencies

The University Grants Commission and the Central Instrumentation Centre, Department of Microbiology, Department of Biotechnology and University College of Pharmaceutical Sciences, Kakatiya University, Warangal, Telangana State, India.

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