European Journal of Chemistry

Microwave synthesis of some N-phenylhydrazine-1-carbothioamide Schiff bases

Article Sidebar

PDF
Published: Jun 30, 2018
DOI: https://doi.org/10.5155/eurjchem.9.2.74-78.1673
Keywords:
Synthesis, Schiff bases, Computational study, Microwave irradiation, 4-Phenylthiosemicarbazide, Carbothioamide derivatives
Section
Research Article
Issue
Vol. 9 No. 2 (2018): June 2018
Dates
Received 2017-11-21
Accepted 2018-03-22
Published 2018-06-30
Crossmark


Main Article Content

Bushra Kamil Al-Salami
Chemistry Department, College of Science, Basrah University, Basrah, 61001, Iraq
http://orcid.org/0000-0002-6023-3071

Abstract

We have synthesized and characterized a series of carbothioamide derivatived molecules, obtained by reaction of aromatic aldehyde (Anisaldehyde, 9-anthraldehyde, cinnamaldehyde, indole-3-carboxaldehyde, 1-naphthaldehyde and o-vanillin) with an equimolar amount of 4-phenylthiosemicarbazide with microwave irradiation. The synthesized compounds have been characterized by FT-IR, 1H NMR and 13C NMR spectroscopy. Quantum calculations of the physical properties, based on density functional theory method at B3LYP/6-31+G(d,p) level of theory, were performed, by means of the Gaussian 09W set of programs. The theoretical 1H NMR chemical shift results of the studied compounds have been calculated at B3LYP method and standard 6-31+G(d,p) basis set using the standard Gauge-Independent Atomic Orbital approach. The calculated values are also compared with the experimental data available for these molecules. A good linear relationship between the experimental and calculated data has been obtained.


icon graph This Abstract was viewed 2037 times | icon graph Article PDF downloaded 898 times

How to Cite
(1)
Al-Salami, B. K. Microwave Synthesis of Some N-Phenylhydrazine-1-Carbothioamide Schiff Bases. Eur. J. Chem. 2018, 9, 74-78.

Article Details

Share
Links for Article


Crossref - Scopus - Google - European PMC
Crossref
Scopus
Google Scholar
Europe PMC
References

[1]. Ebrahimi, H. P.; Hadi, J. S.; Alsalim, T. A.; Ghali, T. S.; Bolandnazer, Z. Spect. Chim. Acta A 2015, 137, 1067-1077.
https://doi.org/10.1016/j.saa.2014.08.146

[2]. Ebrahimi, H. P.; Hadi, J. S.; Almayah, A. A.; Bolandnazar, Z.; Swadi, A. G.; Ebrahimi, A. P. Bioorg. Med. Chem. 2016, 24, 1121-1131.
https://doi.org/10.1016/j.bmc.2016.01.041

[3]. Singh, M. M.; Rastogi, R. B.; Upadhyay, B. N.; Yadav, M. Mater. Chem. Phys. 2003, 80, 283-293.
https://doi.org/10.1016/S0254-0584(02)00513-8

[4]. Al-Salami, B. K.; Mohammed, A. H.; Askar, K. A, Res. J. Pharm. Bio. Chem. 2014, 5(4), 1457-1472.

[5]. Patai, S. The Chemistry of Carbon-Nitrogen Double Bond, John Wiley & Sons Ltd., 1970.
https://doi.org/10.1002/9780470771204

[6]. Loupy, A. Microwaves In Organic Synthesis, Wiley-VCH, Weinheim, 2002.

[7]. Frisch, M. J.; Trucks G. W.; Schlegel, H. B.; Scuseria, G. E.; Robb, M. A.; Cheeseman, J. R.; Scalmani, G.; Barone, V.; Mennucci, B.; Petersson, G. A.; Nakatsuji, H.; Caricato, M.; Li, X.; Hratchian, H. P.; Izmaylov, A. F.; Bloino, J.; Zheng, G.; Sonnenberg, J. L.; Hada, M.; Ehara, M.; Toyota, K.; Fukuda, R.; Hasegawa, J.; Ishida, M.; Nakajima, T.; Honda, Y.; Kitao, O.; Nakai, H.; Vreven, T.; Montgomery, J. A.; Peralta, J. E.; Ogliaro, F.; Bearpark, M.; Heyd, J. J.; Brothers, E.; Kudin, K. N.; Staroverov, V. N.; Kobayashi, R.; Normand, J.; Raghavachari, K.; Rendell, A.; Burant, J. C.; Iyengar, S. S.; Tomasi, J.; Cossi, M.; Rega, N.; Millam, J. M.; Klene, M.; Knox, J. E.; Cross, J. B.; Bakken, V.; Adamo, C.; Jaramillo, J.; Gomperts, R.; Stratmann, R. E.; Yazyev, O.; A. J. Austin, A. J.; Cammi, R.; Pomelli, C.; Ochterski, J. W.; Martin, R. L.; Morokuma, K.; Zakrzewski, V. G; Voth, G. A.; Salvador, P.; Dannenberg, J. J.; Dapprich, S.; Daniels, A. D.; Farkas, O.; Foresman, J. B.; Ortiz, J. V.; Cioslowski, J.; Fox, D. J. Gaussian, Inc. , Gaussian 09, Revision A. 02, Wallingford CT, 2009.

[8]. Shaghaghi, H.; Fathi, F.; Ebrahimi, H. P.; Tafazzoli, M. Conc. Magn. Reson. A 2013, 42(1), 1-13.
https://doi.org/10.1002/cmr.a.21253

[9]. Ebrahimi, H. P.; Tafazzoli, M. Conc. Magn. Reson. A 2013, 42(4), 140-153.
https://doi.org/10.1002/cmr.a.21271

[10]. Dhumad, A. M.; Abood, N. A. J. Basrah Res. (Sci.) 2015, 41(2), 93-106.

[11]. Ebrahimi, H. P.; Hadi, J. S.; Al-Ansari, H. S. J. Mol. Struc. 2013, 1039, 37-45.
https://doi.org/10.1016/j.molstruc.2013.01.063

[12]. Amir, M.; Kumar, S. Acta Pharm. 2007, 57, 31-45.
https://doi.org/10.2478/v10007-007-0003-y

[13]. Hazrati, M. K.; Hadipour, N. L. Comp. Theor. Chem. 2016, 1098, 63-69.
https://doi.org/10.1016/j.comptc.2016.11.007

[14]. Facelli, J. C. Prog. Nucl. Magn. Reson. Spectrosc. 2011, 58(3-4), 176-201.
https://doi.org/10.1016/j.pnmrs.2010.10.003

[15]. Modig, K.; Halle, B. J. Am. Chem. Soc. 2002, 124, 12031-12041.
https://doi.org/10.1021/ja026981s

Supporting Agencies

The Central Laboratory of Esfahan University, Iran
Most read articles by the same author(s)
TrendMD

Dimensions - Altmetric - scite_ - PlumX

Downloads and views

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...
License Terms

License Terms

by-nc

Copyright © 2024 by Authors. This work is published and licensed by Atlanta Publishing House LLC, Atlanta, GA, USA. The full terms of this license are available at https://www.eurjchem.com/index.php/eurjchem/terms and incorporate the Creative Commons Attribution-Non Commercial (CC BY NC) (International, v4.0) License (http://creativecommons.org/licenses/by-nc/4.0). By accessing the work, you hereby accept the Terms. This is an open access article distributed under the terms and conditions of the CC BY NC License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited without any further permission from Atlanta Publishing House LLC (European Journal of Chemistry). No use, distribution, or reproduction is permitted which does not comply with these terms. Permissions for commercial use of this work beyond the scope of the License (https://www.eurjchem.com/index.php/eurjchem/terms) are administered by Atlanta Publishing House LLC (European Journal of Chemistry).