Synthesis, reactions, and applications of chalcones: A review

Nesrin Mahmoud Morsy; Ashraf Sayed Hassan

doi:10.5155/eurjchem.13.2.241-252.2245

PDF

Published: Jun 30, 2022

DOI: https://doi.org/10.5155/eurjchem.13.2.241-252.2245

Keywords:

Synthesis, Reactions, Chalcones, Applications, Chemical method, Biological activity

Section

Review Article

Issue

Vol. 13 No. 2 (2022): June 2022

Dates

Received 2022-03-07
Accepted 2022-04-26
Published 2022-06-30

Nesrin Mahmoud Morsy

Organometallic and Organometalloid Chemistry Department, National Research Centre, Cairo, Dokki 12622, Egypt

https://orcid.org/0000-0003-3636-1767

Ashraf Sayed Hassan

Organometallic and Organometalloid Chemistry Department, National Research Centre, Cairo, Dokki 12622, Egypt

https://orcid.org/0000-0002-4771-716X

Abstract

Considering the essential biological and medicinal properties of chalcones, the synthesis of these compounds has attracted the interest of medicinal and organic chemists. This review aims to describe the different strategies developed so far for the synthesis of chalcones and their applications. After a brief introduction of the chalcones and their biological activities, different synthetic approaches such as chemical and other methods are described and organized on the basis of the catalysts and the other reagents employed in the syntheses. Some of the reactions have been applied successfully to the synthesis of biologically important compounds. Moreover, the biological and pharmacological activities of chalcones have been shown.

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Morsy, N. M.; Hassan, A. S. Synthesis, Reactions, and Applications of Chalcones: A Review. Eur. J. Chem. 2022, 13, 241-252.

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