European Journal of Chemistry

Synthetic applications of benzothiazole containing cyanoacetyl group



Main Article Content

Ahmed Ali Fadda
Fathy Mohamed Abdelrazek
Khaled Samir Mohamed
Howayda Mohamed Mostafa Ghieth
Hassan Ali Etman

Abstract

The reactions of 2-(benzo[d]thiazol-2-yl)-3-oxopentanedinitrile with a variety of reagents have been investigated aiming to explore the synthetic potentialities of this activated nitrile in heterocyclic synthesis. Several novel pyridopyrimidine, chromenopyridine, oxazole, diazepinone, thiophene and thienopyridine derivatives could be obtained starting from 2-(benzo[d]thiazol-2-yl)-3-oxopentanedinitrile and plausible mechanisms for their formations are reported.

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(1)
Fadda, A. A.; Abdelrazek, F. M.; Mohamed, K. S.; Ghieth, H. M. M.; Etman, H. A. Synthetic Applications of Benzothiazole Containing Cyanoacetyl Group. Eur. J. Chem. 2010, 1, 90-95.

Article Details

Author Biographies

Ahmed Ali Fadda, Chemistry Department, Faculty of Science, Mansoura University, Mansoura, 35516, Egypt

Professor of Organic Chemistry, Chemistry Department

Fathy Mohamed Abdelrazek, Chemistry Department, Faculty of Science, Cairo University, Giza, 12613, Egypt

Professor of Organic Chemistry, Chemistry Department
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