European Journal of Chemistry

Synthesis of some pyridyl and cyclohexyl substituted 1,2,4 triazole, 1,3,4-thiadiazole and 1,3,4-oxadiazole derivatives

Article Sidebar

PDF
Published: Dec 22, 2010
DOI: https://doi.org/10.5155/eurjchem.1.4.322-324.65
Keywords:
1, 2, 4-Triazole, 3, 4-Thiadiazole, 4-Oxadiazole, Thiosemicarbazide
Section
Research Article
Issue
Vol. 1 No. 4 (2010): December 2010
Dates
Received 2010-04-16
Accepted 2010-09-26
Published 2010-12-22


Main Article Content

Sattar Ebrahimi
Department of Chemistry, Islamic Azad University, Malayer Branch, IR-65718-117, Iran

Abstract

New 1,2,4-triazoles (4a-c), 1,3,4-thiadiazoles (5a-c) and 1,3,4-oxadiazoles (6a-c) containing isomeric pyridyl and cyclohexyl were synthesized by intramolecular cyclization of 1,4-disubstituted thiosemicarbazides (3a-c) in alkaline media, acid and neutral condition respectively. The chemical structures of newly synthesized compounds were established with help of FT-IR, 1H-NMR and mass spectral data.

1_4_322_324_800


icon graph This Abstract was viewed 1780 times | icon graph Article PDF downloaded 824 times

How to Cite
(1)
Ebrahimi, S. Synthesis of Some Pyridyl and Cyclohexyl Substituted 1,2,4 Triazole, 1,3,4-Thiadiazole and 1,3,4-Oxadiazole Derivatives. Eur. J. Chem. 2010, 1, 322-324.

Article Details

Share
Links for Article


Crossref - Scopus - Google - European PMC
Crossref
Scopus
Google Scholar
Europe PMC
References

[1]. Suresh Kumar, G. V.; Rajendraprasad, Y.; Mallikarjuna, B. P.; Chandrashekar, S. M.; Kistayya, C. Eur. J. Med. Chem. 2010, 45, 2063-2074.
doi:10.1016/j.ejmech.2010.01.045
PMid:20149496

[2]. Mallikarjuna, B. P.; Sastry, B. S.; Suresh Kumar, G. V.; Rajendraprasad, Y.; Chandrashekar, S. M.; Sathisha, K. Eur. J. Med. Chem. 2009, 44, 4739-4746.
doi:10.1016/j.ejmech.2009.06.008
PMid:19589626

[3]. Onkol, T.; Cakir, B.; Sahin, M. F. Turk. J. Chem. 2004, 28, 461-466.

[4]. Schenone, S.; Bruno, O.; Ranise, A.; Bondavalli, F.; Filippeli, W.; Falcone, G.; Giordano, L.; Vitelli, M. R. Bioorg. Med. Chem. 2001, 9, 2149-2153.
doi:10.1016/S0968-0896(01)00121-3

[5]. Holla, B. S.; Gonsalves, R.; Shenoy, S. Eur. J. Med. Chem. 2000, 35, 267– 271.
doi:10.1016/S0223-5234(00)00154-9

[6]. Gokce. M.; Cakir, B.; Erol, K.; Sahin, M. F. Arch. Pharm. 2001, 334, 279-283.

[7]. Laddi, U. V.; Desai, S. R.; Bennur, R. S.; Bennur, S. C. Ind. J. Heterocycl. Chem. 2002, 11, 319–322.

[8]. Sahin, G.; Palaska, E.; Melike Ekizoglu, O. M. Il Farmaco 2002, 57, 539–545.
doi:10.1016/S0014-827X(02)01245-4

[9]. Li, Z.; Gu, Z.; Yin, K.; Zhang, R.; Deng, Q.; Xiang, J. Eur. J. Med. Chem. 2009, 44, 4716-4720.
doi:10.1016/j.ejmech.2009.05.030
PMid:19560842

[10]. Ali, T. A.; El-Kazak, A. M. Eur. J. Chem. 2010, 1(1), 6-11.
doi:10.5155/eurjchem.1.1.6-11.12

[11]. Rollas, S.; Kalyoncuoğlu, N.; Sür-Altiner, D.; Yegenoğlu, Y. Pharmazie 1993, 48, 308-309.
PMid:8321884

[12]. Holla, B. S.; Rao, B. S.; Sarojini, B. K.; Akberali, P. M. Eur. J. Med. Chem. 2004, 39, 777-783.
doi:10.1016/j.ejmech.2004.06.001
PMid:15337290

[13]. Duran, A.; Dogan, H. N.; Rollas S.; Farmaco 2002, 57, 559-564.
doi:10.1016/S0014-827X(02)01248-X

[14]. Sadana, A. K.; Mirza, Y.; Aneja, K. R.; Prakash, O. Eur. J. Med. Chem. 2003, 38, 533-538.
doi:10.1016/S0223-5234(03)00061-8

[15]. Vu, C. B.; Shields, P.; Peng, B.; Kumaravel, G.; Jin, X.; Phadke, D.; Wang, J.; Engber, T.; Ayyub, E.; Petter, R. Bioorg. Med. Chem. Lett. 2004, 14, 4835-838.
doi:10.1016/j.bmcl.2004.07.048

[16]. Ilango, K.; Valentina, P. Eur. J. Chem. 2010, 1(1), 50-53.
doi:10.5155/eurjchem.1.1.50-53.4

[17]. Foroughifar, N.; Mobinikhaledi, A.; Ebrahimi, S. Synthesis 2009, 15, 2557-2560.
doi:10.1055/s-0029-1217398

[18]. Mobinikhaledi, A.; Foroughifar, N.; Khanpour, M.; Ebrahimi, S. Eur. J. Chem. 2010, 1(1), 33-36.
doi:10.5155/eurjchem.1.1.33-36.5

[19]. Foroughifar, N.; Mobinikhaledi, A.; Ebrahimi, S.; Moghanian, H.; Bodaghi Fard, M. A.; Kalhor, M. Tetrahedron Lett. 2009, 50, 836-839.
doi:10.1016/j.tetlet.2008.12.014

[20]. Foroughifar, N.; Mobinikhaledi, A.; Ebrahimi, S.; Bodaghi Fard, M. A.; Moghanian, M. J. Chin. Chem. Soc. 2009, 56, 1043-1047.

[21]. Foroughifar, N.; Mobinikhaledi, A.; Ebrahimi, S. Synthetic Commun. 2010, 40, 2421-2428.
doi:10.1080/00397910903261387

[22]. Zamani, Kh.; Faghihi, Kh.; Tofighi, T. Turk. J. Chem. 2004, 28, 95-100.

Supporting Agencies

Most read articles by the same author(s)

Most read articles by the same author(s)

TrendMD

Dimensions - Altmetric - scite_ - PlumX

Downloads and views

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...
License Terms

License Terms

by-nc

Copyright © 2024 by Authors. This work is published and licensed by Atlanta Publishing House LLC, Atlanta, GA, USA. The full terms of this license are available at https://www.eurjchem.com/index.php/eurjchem/terms and incorporate the Creative Commons Attribution-Non Commercial (CC BY NC) (International, v4.0) License (http://creativecommons.org/licenses/by-nc/4.0). By accessing the work, you hereby accept the Terms. This is an open access article distributed under the terms and conditions of the CC BY NC License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited without any further permission from Atlanta Publishing House LLC (European Journal of Chemistry). No use, distribution, or reproduction is permitted which does not comply with these terms. Permissions for commercial use of this work beyond the scope of the License (https://www.eurjchem.com/index.php/eurjchem/terms) are administered by Atlanta Publishing House LLC (European Journal of Chemistry).