European Journal of Chemistry

Synthesis, characterization and antibacterial activity of (E)-chalcone derivatives

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Published: Sep 30, 2013
DOI: https://doi.org/10.5155/eurjchem.4.3.207-210.780
Keywords:
Furan derivatives, Meerwein's reaction, Chalcone derivatives, Antibacterial activity, Claisen-Schmidt condensation, 1, 3-Diphenyl-2-propen-1-ones
Section
Research Article
Issue
Vol. 4 No. 3 (2013): September 2013
Dates
Received 2013-03-23
Accepted 2013-04-23
Published 2013-09-30


Main Article Content

Ahmed Mutanabbi Abdula
Chemistry Department, College of Science, Al-Mustansiriyah University, Baghdad, 00964, Iraq

Abstract

(E)-Chalcone derivatives were synthesized by the Claisen-Schmidt condensation of aromatic aldehydes with methyl ketones. 5-Arylfuran-2-carboxaldehydes (1a-b) were synthesized by Meerwein´s method and condensed with 2-acetylpyrole or 2-acetylfuran to produce the new chalcone derivatives (2a-d). The new chalcones were characterized using FT-IR and GC-MS. The synthesized compounds were also screened against some bacterial species to evaluate their activity as promising antibacterial agents.

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Abdula, A. M. Synthesis, Characterization and Antibacterial Activity of (E)-Chalcone Derivatives. Eur. J. Chem. 2013, 4, 207-210.

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Chemistry Department, College of Science, Al-Mustansiriyah University, Baghdad, Iraq
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