IL-17 level in patients with acute myocardial infarction and  its effect on lipid profile

Ammal Esmaeel Ibrahim; Hiba Ali Hasan; Alaa Hussein Jawad

doi:10.5155/eurjchem.5.1.186-188.938

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Published: Mar 30, 2014

DOI: https://doi.org/10.5155/eurjchem.5.1.186-188.938

Keywords:

IL-17, Triglycerides, Total cholesterol, Low density lipoprotein, High density lipoprotein, Acute myocardial infarction

Section

Research Article

Issue

Vol. 5 No. 1 (2014): March 2014

Dates

Received 2013-09-27
Accepted 2013-10-26
Published 2014-03-30

Ammal Esmaeel Ibrahim

Department of Chemistry, College of Science, Al-Nahrain University, Baghdad, 10072, Iraq

Hiba Ali Hasan

Department of Clinical Laboratory Science, Collage of Pharmacy, Al-Mustansiriya University, Baghdad, 10052, Iraq

Alaa Hussein Jawad

Department of Chemistry, College of Science, Al-Nahrain University, Baghdad, 10072, Iraq

Abstract

Myocardial infarction (MI) is considered as the major cause of death and disability worldwide, and despite considerable advances in diagnosis and treatment, continues to be a major public health problem. Interleukin-17 (IL-17) is leukocyte-derived cytokine with effects especially on epithelial cells in various tissues. This study designed to investigate the level of IL-17 and its effect on lipid profile in patients with Acute Myocardial Infarction. The study included 50 patients with acute myocardial infarction forty healthy subjects as control group. The levels of IL-17 were significantly elevated in all patients groups (p < 0.001), total cholesterol, LDL, VLDL were significantly elevated (p < 0.001) in all patients as well. There was positive correlation between IL-17 with HDL, while there was negative correlation with total cholesterol and LDL. The results show significant increase in levels of IL-17, in acute myocardial infarction patients. IL-17 positively correlated with HDL and negatively correlated with total cholesterol and LDL, which lead to consider it as cardio protective factor.

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How to Cite

(1)

Ibrahim, A. E.; Hasan, H. A.; Jawad, A. H. IL-17 Level in Patients With Acute Myocardial Infarction and Its Effect on Lipid Profile. Eur. J. Chem. 2014, 5, 186-188.

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