European Journal of Chemistry

Synthesis, structural elucidation and X-ray crystallographic studies of 1-(3,5-bis(trifluoromethyl)phenyl)-3-(dimethylamino)prop-2-en-1-one

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Published: Dec 31, 2019
DOI: https://doi.org/10.5155/eurjchem.10.4.381-385.1922
Keywords:
Enaminones, Acetophenone, Trifluoromethyl, X-ray crystallography, Geometric parameters, N, N-Dimethylformamide dimethyl acetal
Section
Research Article
Issue
Vol. 10 No. 4 (2019): December 2019
Dates
Received 2019-09-03
Accepted 2019-10-06
Published 2019-12-31
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Stability Nongrum
Organic Research Laboratory, Department of Chemical Science, Assam Don Bosco University, Tapesia Gardens, Kamarkuchi, Sonapur, 782 402 Assam, India
http://orcid.org/0000-0002-2427-6007
Susma Das
Organic Research Laboratory, Department of Chemical Science, Assam Don Bosco University, Tapesia Gardens, Kamarkuchi, Sonapur, 782 402 Assam, India
http://orcid.org/0000-0002-2391-8792
Shikpika Khanikar
Organic Research Laboratory, Department of Chemical Science, Assam Don Bosco University, Tapesia Gardens, Kamarkuchi, Sonapur, 782 402 Assam, India
http://orcid.org/0000-0001-9845-2002
Jai Narain Vishwakarma
Organic Research Laboratory, Department of Chemical Science, Assam Don Bosco University, Tapesia Gardens, Kamarkuchi, Sonapur, 782 402 Assam, India
http://orcid.org/0000-0001-9068-4554

Abstract

A new enaminone was synthesized by reacting 3,5-bis-(trifluoromethyl)acetophenones and N,N-dimethylformamide dimethyl acetal and its detailed structural and crystalline properties were studied. The crystal data were found to be as C13H11F6NO, monoclinic, space group P21/c (no. 14), a = 8.1556(8) Å, b = 24.877(3) Å, c = 7.6067(7) Å, β = 116.745(6)°, V = 1378.2(3) Å3, Z = 4, T = 293(2) K, μ(MoKα) = 0.150 mm-1, Dcalc = 1.500 g/cm3, 40777 reflections measured (5.594° ≤ 2Θ ≤ 56.786°), 3413 unique (Rint = 0.1040, Rsigma = 0.0584) which were used in all calculations. The final R1 was 0.0771 (I > 2σ(I)) and wR2 was 0.2541 (all data).


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Nongrum, S.; Das, S.; Khanikar, S.; Vishwakarma, J. N. Synthesis, Structural Elucidation and X-Ray Crystallographic Studies of 1-(3,5-bis(trifluoromethyl)phenyl)-3-(dimethylamino)prop-2-En-1-One. Eur. J. Chem. 2019, 10, 381-385.

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Department of Biotechnology, Government of India, India.
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