European Journal of Chemistry

Synthesis, reactions and biological evaluation of benzyltriazolophthalazine derivatives

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Published: Mar 31, 2013
DOI: https://doi.org/10.5155/eurjchem.4.1.10-19.707
Keywords:
Thioglycolic acid, Aromatic aldehyde, Knoevenagal reaction, Cyanoacetohydrazide, Antimicrobial activity, 4-Benzyl-1-chlorophthalazine
Section
Research Article
Issue
Vol. 4 No. 1 (2013): March 2013
Dates
Received 2012-11-09
Accepted 2012-12-17
Published 2013-03-31


Main Article Content

Ashraf Hassan Fekry Abd El-Wahab
Chemistry Department, Faculty of Science, Al-Azhar University, 11884, Nasr City, Cairo, Egypt
Hany Mostafa Mohamed
Chemistry Department, Faculty of Medicine, Jazan University, 82621, Jazan, Saudi Arabia
Ahmed Mohamed El-Agrody
Chemistry Department, Faculty of Science, King Khalid University, 9004, Abha, Saudi Arabia
Mohamed Ahmed El-Nassag
Chemistry Department, Faculty of Science, Al-Azhar University, 11884, Nasr City, Cairo, Egypt
Ahmed Hammam Bedair
Chemistry Department, Faculty of Science, Al-Azhar University, 11884, Nasr City, Cairo, Egypt

Abstract

A series of triazolophthalazine derivatives (4-22) were synthesized and characterized. The structures of the newly synthesized compounds were confirmed by spectral data. The newly synthesized compounds were also screened for their antimicrobial activity.

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El-Wahab, A. H. F. A.; Mohamed, H. M.; El-Agrody, A. M.; El-Nassag, M. A.; Bedair, A. H. Synthesis, Reactions and Biological Evaluation of Benzyltriazolophthalazine Derivatives. Eur. J. Chem. 2013, 4, 10-19.

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