European Journal of Chemistry

An environmentally benign and efficient synthesis of 2-thio-substituted benzothiazoles

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Published: Jun 30, 2014
DOI: https://doi.org/10.5155/eurjchem.5.2.291-295.861
Keywords:
CuFe2O4, PEG-400, Benzothiazole, Iodo benzenes, Magnetically separable, 2-Mercapto benzothiazole
Section
Research Article
Issue
Vol. 5 No. 2 (2014): June 2014
Dates
Received 2013-06-24
Accepted 2013-07-31
Published 2014-06-30


Main Article Content

Gaddam Satish
Council of Scientific and Industrial Research, Medicinal Chemistry and Pharmacology Division, Indian Institute of Chemical Technology, Uppal Road, Hyderabad 500-007, India
Kasireddy Harsha Vardhan Reddy
Council of Scientific and Industrial Research, Medicinal Chemistry and Pharmacology Division, Indian Institute of Chemical Technology, Uppal Road, Hyderabad 500-007, India
Katla Ramesh
Council of Scientific and Industrial Research, Medicinal Chemistry and Pharmacology Division, Indian Institute of Chemical Technology, Uppal Road, Hyderabad 500-007, India
Jilla Shankar
Council of Scientific and Industrial Research, Medicinal Chemistry and Pharmacology Division, Indian Institute of Chemical Technology, Uppal Road, Hyderabad 500-007, India
Yadavalli Venkata Durga Nageswar
Council of Scientific and Industrial Research, Medicinal Chemistry and Pharmacology Division, Indian Institute of Chemical Technology, Uppal Road, Hyderabad 500-007, India

Abstract

An environmentally benign, simple and highly efficient method for the synthesis of 2-thio-substituted benzothiazole derivatives has been achieved in good to excellent yields by reacting a series of aryl halides with 2-mercapto benzothiazole, using recyclable CuFe2O4 nanoparticles under ligand free conditions in PEG-400 as solvent. In the present protocol, the copper ferrite nanoparticles can be recovered and reused up to four cycles without significant loss of activity.


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How to Cite
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Satish, G.; Reddy, K. H. V.; Ramesh, K.; Shankar, J.; Nageswar, Y. V. D. An Environmentally Benign and Efficient Synthesis of 2-Thio-Substituted Benzothiazoles. Eur. J. Chem. 2014, 5, 291-295.

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Council of Scientific and Industrial Research, New Delhi, India
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