Synthesis of pyrazoline derivatives from the 1,3-dipolar cycloadditions using α,β-unsaturated cyclohexanone derivatives

Nouara Ziani; Kaddour Lamara; Assia Sid; Quentin Willem; Benjamin Dassonneville; Albert Demonceau

doi:10.5155/eurjchem.4.2.176-179.757

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Published: Jun 30, 2013

DOI: https://doi.org/10.5155/eurjchem.4.2.176-179.757

Keywords:

Acetic acid, Pyrazolines, Spectroscopy, Hydrazine hydrate, 1, 3-Dipolar cycloadditions, α, β-Unsaturated cyclohexanone derivatives

Section

Research Article

Issue

Vol. 4 No. 2 (2013): June 2013

Dates

Received 2013-02-21
Accepted 2013-04-05
Published 2013-06-30

Nouara Ziani

Département de Chimie, Faculté des Sciences, Université Ferhat Abbas, Sétif, 19000, Algérie

Kaddour Lamara

Laboratory of Applied Chemistry and Materials Technology, Chemistry Institute, University Larbi Ben M’hidi of Oum El Bouaghi, Rue de Constantine, 04000, Algeria

Assia Sid

Laboratory of Applied Chemistry and Materials Technology, Chemistry Institute, University Larbi Ben M’hidi of Oum El Bouaghi, Rue de Constantine, 04000, Algeria

Quentin Willem

Laboratoire de Chimie Macromoléculaire et de Catalyse Organique, Département de Chimie, Université de Liège, Sart-Tilman (B.6a), B-4000 Liège, Belgique

Benjamin Dassonneville

Laboratoire de Chimie Macromoléculaire et de Catalyse Organique, Département de Chimie, Université de Liège, Sart-Tilman (B.6a), B-4000 Liège, Belgique

Albert Demonceau

Laboratoire de Chimie Macromoléculaire et de Catalyse Organique, Département de Chimie, Université de Liège, Sart-Tilman (B.6a), B-4000 Liège, Belgique

Abstract

A series of 2-pyrazolines (3a-d) were obtained by reaction 1,3-dipolar cycloadditions of α,β-unsaturated cyclohexanone derivatives (2a-c) with hydrazine hydrate and 4-nitrophenylhydrazine in the presence of acetic acid and ethanol as solvents. The structures of the synthesized compounds were confirmed by spectroscopic methods; IR, ¹H and ¹³C NMR.

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How to Cite

(1)

Ziani, N.; Lamara, K.; Sid, A.; Willem, Q.; Dassonneville, B.; Demonceau, A. Synthesis of Pyrazoline Derivatives from the 1,3-Dipolar Cycloadditions Using α,β-Unsaturated Cyclohexanone Derivatives. Eur. J. Chem. 2013, 4, 176-179.

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Supporting Agencies

Laboratory of Applied Chemistry and Materials Technology, Chemistry Institute, University Larbi Ben M’hidi of Oum El Bouaghi, Rue de Constantine, 04000, Algeria.

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