European Journal of Chemistry

Synthesis of pyrazoline derivatives from the 1,3-dipolar cycloadditions using α,β-unsaturated cyclohexanone derivatives

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Nouara Ziani
Kaddour Lamara
Assia Sid
Quentin Willem
Benjamin Dassonneville
Albert Demonceau


A series of 2-pyrazolines (3a-d) were obtained by reaction 1,3-dipolar cycloadditions of α,β-unsaturated cyclohexanone derivatives (2a-c) with hydrazine hydrate and 4-nitrophenylhydrazine in the presence of acetic acid and ethanol as solvents. The structures of the synthesized compounds were confirmed by spectroscopic methods; IR, 1H and 13C NMR.


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Ziani, N.; Lamara, K.; Sid, A.; Willem, Q.; Dassonneville, B.; Demonceau, A. Synthesis of Pyrazoline Derivatives from the 1,3-Dipolar Cycloadditions Using α,β-Unsaturated Cyclohexanone Derivatives. Eur. J. Chem. 2013, 4, 176-179.

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Supporting Agencies

Laboratory of Applied Chemistry and Materials Technology, Chemistry Institute, University Larbi Ben M’hidi of Oum El Bouaghi, Rue de Constantine, 04000, Algeria.
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