Synthesis, antifungal activity and semi-empirical AM1-MO calculations of some new 4-oxo-4H-chromene derivatives | European Journal of Chemistry

Default Image

PDF

Published: Jun 30, 2011

DOI: https://doi.org/10.5155/eurjchem.2.2.158-162.381

Keywords:

Synthesis, Chromone, Chromone Derivatives, 3-Formylchromones, Antifungal activity, AM1-MO Calculation

Section

Research Article

Issue

Vol. 2 No. 2 (2011): June 2011

Dates

Received 2011-01-01
Accepted 2011-02-09
Published 2011-06-30

Hafez Mohamed El-Shaaer

eMail

Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, 11711, Cairo, Egypt

Salah Abdel-Ghaffar Abdel-Aziz

eMail

Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, 11711, Cairo, Egypt

Faten Ismail Hanafy

eMail

Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, 11711, Cairo, Egypt

Tarik El-Sayed Ali

eMail

Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, 11711, Cairo, Egypt

Ali Zaky El-Fauomy

eMail

Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, 11711, Cairo, Egypt

Abstract

Some new antifungal agents have been prepared through reaction of 4-oxo-4H-chromene-3-carbaldehydes (1a,b) with some active primary amines (2a-e) and amides/thioamides (6a-d) in different conditions. Structures of the products were established on the basis of elemental analysis, IR, ¹H NMR, mass spectra and semi-empirical AM1-MO calculations. 2_2_158_162_800

2_2_158_162_800

This Abstract was viewed 2914 times |

Article PDF downloaded 942 times

How to Cite

(1)

El-Shaaer, H. M.; Abdel-Aziz, S. A.-G.; Hanafy, F. I.; Ali, T. E.-S.; El-Fauomy, A. Z. Synthesis, Antifungal Activity and Semi-Empirical AM1-MO Calculations of Some New 4-Oxo-4H-Chromene Derivatives. Eur. J. Chem. 2011, 2, 158-162.

Share

Links for Article

Crossref - Scopus - Google - European PMC

Crossref

Scopus

Google Scholar

Europe PMC

References

[1]. Ellis, G. P. Chromenes, Chromanones, and Chromones. The Chemistry of Heterocyclic Compounds; Wiley: New York, NY, Vol. 31, 1977.

[2]. Horton, D. A.; Bourne, G. T.; Smythe, M. L. Chem. Rev. 2003, 103, 893-930.
PMid:18778828

[3]. Langer, P. Synlett 2007, 7, 1016-1025.
PMid:18247406

[4]. Ali, T. E.; Abdel-Aziz, S. A.; El-Shaaer, H. M.; Hanafy, F. I.; El-Fauomy A. Z. Phosphorus, Sulfur and Silicon and the Relat. Elem. 2008, 183, 2139-2160.
PMid:19410412

[5]. Ibrahim, A. M.; Ali, T. E. J. Brazilian Chem. Soc. 2010, 2, 1007-1016.
PMid:19173350

[6]. Ghosh, C. K.; Patra, A. J. Heterocycl. Chem. 2008, 45, 1529-1547.
PMid:20018473

[7]. Sosnovskikh, V. Y.; Moshkin, V. S.; Kodess, M. I. Tetrahedron 2008, 64, 7877-7889.
PMid:20554147

[8]. Sosnovskikh, V. Y.; Irgashev, R. A.; Moshkin, V. S.; Kodess, M. I. Russ. Chem. Bull., Intern. Edition 2008, 57, 2146-2151.

[9]. El-Shaaer, H. M.; Zahradnik, P.; Lacova, M.; Matulova, M. Collect. Czech. Commun. 1994, 59, 1673-1681.

[10]. Melikyan, G. S.; Lacova, M.; Kralova, K.; El-Shaaer, H. M.; Henselova, M.; Avetisyan, A. A. Chem. Papers 1993, 47, 388-392.
PMCid:1176066

[11]. El-Shaaer, H. M.; Perjessy, A.; Zahradnik, P.; Lacova, M.; Sustekova, Z. Monatsh. Chem. 1993,124, 539-548.

[12]. Ali, T. E. Phosphorus, Sulfur, Silicon and Relat. Elem. 2007, 182, 1717-1726.
PMid:16542666

[13]. Ali, T. E.; Abdel-Aziz, S. A.; El-Shaaer, H. M.; Hanafy, F. I.; El-Fauomy, A. Z. Turk. J. Chem. 2008, 32, 365-374.

[14]. Lácová, M.; Gašparová, R.; Koiš, P.; Boháč, A.; El-Shaaer, H. M. Tetrahedron 2010, 66, 1410-1419.

[15]. Nohara, A.; Umetani, T.; Sanno, Y. Tetrahedron 1974, 30(19), 3553-3561.
PMid:19125430

[16]. Hassan, A. Y. Phosphorus, Sulfur, Silicon and the Relat. Elem. 2009, 184, 2759-2776.

[17]. Dornow, A.; Menzel, M. P. Chem. Ber. 1964, 97, 2173-2178.
PMid:9229718

[18]. Hania, M. M. E-Journal of Chemistry 2009, 6(S1), S508-S514.

[19]. Schiemenz, G. P. Chem. Ber. 1962, 95, 483-486.

[20]. Stankovicova, H.; Lacova, M.; Gaplovsky, A.; Chovancova, J.; Pronayova, N. Tetrahedron 2001, 57, 3455-3464.

[21]. Lacova, M.; Stankovicova, H.; Odlerova, Z. Farmaco 1995, 50(12), 885-888.

[22]. Rahman, A. U.; Choudhary, M. I.; Thomsen, W. J. Bioassay Techniques for Drug Development, Harwood Academic Publishers: The Netherlands 2001.

Supporting Agencies

Most read articles by the same author(s)

Most read articles by the same author(s)

Tarik El-Sayed Ali, Azza Mohammed El-Kazak, Synthesis and antimicrobial activity of some new 1,3-thiazoles, 1,3,4-thiadiazoles, 1,2,4-triazoles and 1,3-thiazines incorporating acridine and 1,2,3,4-tetrahydroacridine moieties , European Journal of Chemistry: Vol. 1 No. 1 (2010): March 2010
Tarik El-Sayed Ali, Magdy Ahmed Ibrahim, Nasser Mohamed El-Gohary, Azza Mohamed El‐Kazak, 3-Formylchromones as diverse building blocks in heterocycles synthesis , European Journal of Chemistry: Vol. 4 No. 3 (2013): September 2013
Reda Mohammady Abdel-Rahman, Mohammed Saleh Tawfik Makki, Tarik El-Sayed Ali, Magdy Ahmed Ibrahim, 1,2,4-Triazine Chemistry Part I: Orientation of cyclization reactions of functionalized 1,2,4-triazine derivatives , European Journal of Chemistry: Vol. 1 No. 3 (2010): September 2010
Salah Abdel-Ghaffar Abdel-Aziz, Tarik El-Sayed Ali, Kamilia Mohamed El-Mahdy, Somaia Mohamed Abdel-Karim, Synthesis and antimicrobial activities of some novel bis-pyrazole derivatives containing a hydrophosphoryl unit , European Journal of Chemistry: Vol. 2 No. 1 (2011): March 2011
Reda Mohammady Abdel-Rahman, Magdy Ahmed Ibrahim, Tarik El-Sayed Ali, 1,2,4-Triazine Chemistry Part II: Synthetic approaches for phosphorus containing 1,2,4-triazine derivatives , European Journal of Chemistry: Vol. 1 No. 4 (2010): December 2010
Hafez Mohamed El-Shaaer, An efficient synthesis of some new isolated and fused 2-oxo-2H-chromene derivatives as antimicrobial and antitumor agents , European Journal of Chemistry: Vol. 4 No. 2 (2013): June 2013
Hafez Mohamed El-Shaaer, Salah Sayed Ibrahim, Wafaa Ramzy Abd-Elmonem, Christine Gamal Ibrahim, An efficient cyclocondensation reactions, antimicrobial activity and molecular orbital calculations of α-benzopyrone derivatives , European Journal of Chemistry: Vol. 3 No. 2 (2012): June 2012
Hafez Mohamed El-Shaaer, Cyclocondensation, antimicrobial activity and semi-empirical AM1-MO calculations of benzopyrone derivatives , European Journal of Chemistry: Vol. 3 No. 1 (2012): March 2012

TrendMD

Dimensions - Altmetric - scite_ - PlumX

Downloads and views

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

License Terms

License Terms

by-nc

Copyright © 2024 by Authors. This work is published and licensed by Atlanta Publishing House LLC, Atlanta, GA, USA. The full terms of this license are available at https://www.eurjchem.com/index.php/eurjchem/terms and incorporate the Creative Commons Attribution-Non Commercial (CC BY NC) (International, v4.0) License (http://creativecommons.org/licenses/by-nc/4.0). By accessing the work, you hereby accept the Terms. This is an open access article distributed under the terms and conditions of the CC BY NC License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited without any further permission from Atlanta Publishing House LLC (European Journal of Chemistry). No use, distribution, or reproduction is permitted which does not comply with these terms. Permissions for commercial use of this work beyond the scope of the License (https://www.eurjchem.com/index.php/eurjchem/terms) are administered by Atlanta Publishing House LLC (European Journal of Chemistry).