European Journal of Chemistry

1,2,4-Triazine Chemistry Part I: Orientation of cyclization reactions of functionalized 1,2,4-triazine derivatives



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Reda Mohammady Abdel-Rahman
Mohammed Saleh Tawfik Makki
Tarik El-Sayed Ali
Magdy Ahmed Ibrahim

Abstract

Orientation of heterocyclization reactions of functionalized 1,2,4-triazines were studied by effect of substituents in 1,2,4-triazine moieties, type of the solvent used in the reaction and the temperature effect. Also, it was found that cyclization process depended mainly on the chemoselective and regioselectivity states of the parent substrate as well as preferring cite of ring closure.

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Abdel-Rahman, R. M.; Makki, M. S. T.; Ali, T. E.-S.; Ibrahim, M. A. 1,2,4-Triazine Chemistry Part I: Orientation of Cyclization Reactions of Functionalized 1,2,4-Triazine Derivatives. Eur. J. Chem. 2010, 1, 236-245.

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