European Journal of Chemistry 2010, 1(3), 236-245. doi:https://doi.org/10.5155/eurjchem.1.3.236-245.54

1,2,4-Triazine Chemistry Part I: Orientation of cyclization reactions of functionalized 1,2,4-triazine derivatives


Reda Mohammady Abdel-Rahman (1) , Mohammed Saleh Tawfik Makki (2) , Tarik El-Sayed Ali (3,*) , Magdy Ahmed Ibrahim (4)

(1) Department of Chemistry, Faculty of Science, King Abdel-Aziz University, Jeddah, 21589, Saudi Arabia
(2) Department of Chemistry, Faculty of Science, King Abdel-Aziz University, Jeddah, 21589, Saudi Arabia
(3) Department of Chemistry, Faculty of Education, Ain shams University, Roxy, 11711, Cairo, Egypt
(4) Department of Chemistry, Faculty of Education, Ain shams University, Roxy, 11711, Cairo, Egypt
(*) Corresponding Author

Received: 10 Apr 2010, Accepted: 29 Jun 2010, Published: 29 Sep 2010

Abstract


Orientation of heterocyclization reactions of functionalized 1,2,4-triazines were studied by effect of substituents in 1,2,4-triazine moieties, type of the solvent used in the reaction and the temperature effect. Also, it was found that cyclization process depended mainly on the chemoselective and regioselectivity states of the parent substrate as well as preferring cite of ring closure.

1_3_236_245_800


Keywords


1,2,4-Triazines; Chemical reactivity; Cyclization reactions

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DOI: 10.5155/eurjchem.1.3.236-245.54

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[1]. Reda Mohammady Abdel-Rahman, Mohammed Saleh Tawfik Makki, Tarik El-Sayed Ali, Magdy Ahmed Ibrahim
ChemInform Abstract: 1,2,4-Triazine Chemistry. Part 1. Orientation of Cyclization Reactions of Functionalized 1,2,4-Triazine Derivatives
ChemInform  42(48), no, 2011
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[2]. Reda M. Abdel-Rahman, Abdullah M. Asiri, Salman A. Khan
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[3]. Galina A. Gazieva, Alexei N. Izmest'ev, Yulia V. Nelyubina, Natalya G. Kolotyrkina, Igor E. Zanin, Angelina N. Kravchenko
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[6]. Wen-Bin Chen, Zhi-Xin Li, Xin-Wei Yu, Meng Yang, Yan-Xuan Qiu, Wen Dong
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How to cite


Abdel-Rahman, R.; Makki, M.; Ali, T.; Ibrahim, M. Eur. J. Chem. 2010, 1(3), 236-245. doi:https://doi.org/10.5155/eurjchem.1.3.236-245.54
Abdel-Rahman, R.; Makki, M.; Ali, T.; Ibrahim, M. Eur. J. Chem. 1,2,4-Triazine Chemistry Part I: Orientation of cyclization reactions of functionalized 1,2,4-triazine derivatives. 2010, 1(3), 236-245. doi:https://doi.org/10.5155/eurjchem.1.3.236-245.54
Abdel-Rahman, R., Makki, M., Ali, T., & Ibrahim, M. (2010). 1,2,4-Triazine Chemistry Part I: Orientation of cyclization reactions of functionalized 1,2,4-triazine derivatives. European Journal of Chemistry, 1(3), 236-245. doi:https://doi.org/10.5155/eurjchem.1.3.236-245.54
Abdel-Rahman, Reda, Mohammed Saleh Tawfik Makki, Tarik El-Sayed Ali, & Magdy Ahmed Ibrahim. "1,2,4-Triazine Chemistry Part I: Orientation of cyclization reactions of functionalized 1,2,4-triazine derivatives." European Journal of Chemistry [Online], 1.3 (2010): 236-245. Web. 19 Jun. 2018
Abdel-Rahman, Reda, Makki, Mohammed, Ali, Tarik, AND Ibrahim, Magdy. "1,2,4-Triazine Chemistry Part I: Orientation of cyclization reactions of functionalized 1,2,4-triazine derivatives" European Journal of Chemistry [Online], Volume 1 Number 3 (29 September 2010)

DOI: https://doi.org/10.5155/eurjchem.1.3.236-245.54

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