Reactions with hydrazonoyl halides 66: Synthesis of some new  1,3,4-thiadiazoles, triazolino[4,3-a]pyrimidines and  isoxazolo[3,4-d]pyridazines containing coumarin moiety

Abdou Osman Abdelhamid; Abdelgawad Ali Fahmi; Abeer Bahlol Ali

doi:10.5155/eurjchem.2.4.544-551.478

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Published: Dec 31, 2011

DOI: https://doi.org/10.5155/eurjchem.2.4.544-551.478

Keywords:

Coumarins, Nitrilimines, 1, 3, 4-Thiadiazoles, Pyrimidine-2-thione, Isoxazolo[3, 4-d]prymidines, Triazolino[4, 3-a]pyrimidines

Section

Research Article

Issue

Vol. 2 No. 4 (2011): December 2011

Dates

Received 2011-06-10
Accepted 2011-07-22
Published 2011-12-31

Abdou Osman Abdelhamid

Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt

Abdelgawad Ali Fahmi

Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt

Abeer Bahlol Ali

Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt

Abstract

2,3-Dihydro-1,3,4-thiadiazoles, triazolino[4,3-a]pyrimidines, isoxazoles and isoxazolo[3,4-d]pyridazines containing coumarin moities were synthesized from the reactions of methyl (or benzyl) carbodithioate, pyrimidine-2-thione and 3-(3-(dimethylamino)acryloyl)-2H-chromen-2-one derivatives with C-coumarinoyl-N-phenylhydrazonoyl bromide. The structures of all the newly synthesized compounds were confirmed by elemental analyses and spectral data.

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Abdelhamid, A. O.; Fahmi, A. A.; Ali, A. B. Reactions With Hydrazonoyl Halides 66: Synthesis of Some New 1,3,4-Thiadiazoles, triazolino[4,3-a]pyrimidines and isoxazolo[3,4-d]pyridazines Containing Coumarin Moiety. Eur. J. Chem. 2011, 2, 544-551.

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